NTH1 (NTHL1) (NM_002528) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. [provided by RefSeq, Oct 2008]

• Synonyms:

  FAP3; hNTH1; NTH1; OCTS3

• Gene ID:

  4913

• UniProt:

  P78549, E5KTI5

• Accession Number mRNA:

  NM_002528

• Chromosomal Location:

  16p13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Base excision repair

• Field of Research:

  Base excision repair

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Stem cell - Pluripotency

• Molecular Weight:

  34.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NTHL1

• Species:

  Human

• Protein ID:

  NP_002519

• Overview:

  Recombinant protein of human nth endonuclease III-like 1 (E. coli) (NTHL1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4913

• Uniprot URL:

  https://www.uniprot.org/uniprot/P78549

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002528

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002519