FGF14 (NM_004115) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  FGF-14; FHF-4; FHF4; SCA27

• Gene ID:

  2259

• UniProt:

  Q92915

• Accession Number mRNA:

  NM_004115

• Chromosomal Location:

  13q33.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

• Field of Research:

  MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein

• Molecular Weight:

  27.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FGF14

• Species:

  Human

• Protein ID:

  NP_004106

• Overview:

  Recombinant protein of human fibroblast growth factor 14 (FGF14), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2259

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q92915

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004115

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004106