EED (NM_003797) Human Recombinant Protein

• Background:

  This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  COGIS; HEED; WAIT1

• Gene ID:

  8726

• UniProt:

  O75530

• Accession Number mRNA:

  NM_003797

• Chromosomal Location:

  11q14.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  50 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EED

• Species:

  Human

• Protein ID:

  NP_003788

• Overview:

  Recombinant protein of human embryonic ectoderm development (EED), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8726

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75530

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003797

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003788