BRD8 (NM_139199) Human Recombinant Protein

• Background:

  The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Multiple alternatively spliced transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2014]

• Synonyms:

  P120; SMAP; SMAP2

• Gene ID:

  10902

• UniProt:

  Q9H0E9

• Accession Number mRNA:

  NM_139199

• Chromosomal Location:

  5q31.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  135.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  BRD8

• Species:

  Human

• Protein ID:

  NP_631938

• Overview:

  Recombinant protein of human bromodomain containing 8 (BRD8), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10902

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H0E9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_139199

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_631938