FADS2 (NM_004265) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

• Synonyms:

  D6D; DES6; FADSD6; LLCDL2; SLL0262; TU13

• Gene ID:

  9415

• UniProt:

  O95864

• Accession Number mRNA:

  NM_004265

• Chromosomal Location:

  11q12.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Alpha-Linolenic acid metabolism, Biosynthesis of unsaturated fatty acids, PPAR signaling pathway

• Field of Research:

  Alpha-Linolenic acid metabolism, Biosynthesis of unsaturated fatty acids, PPAR signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  52.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FADS2

• Species:

  Human

• Protein ID:

  NP_004256

• Overview:

  Recombinant protein of human fatty acid desaturase 2 (FADS2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9415

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95864

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004265

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004256