Sialoadhesin (SIGLEC1) (NM_023068) Human Recombinant Protein

• Background:

  This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

• Synonyms:

  CD169; dJ1009E24.1; SIGLEC-1; SN

• Gene ID:

  6614

• UniProt:

  Q9BZZ2

• Accession Number mRNA:

  NM_023068

• Chromosomal Location:

  20p13

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell adhesion molecules (CAMs)

• Field of Research:

  Cell adhesion molecules (CAMs)

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  180.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SIGLEC1

• Species:

  Human

• Protein ID:

  NP_075556

• Overview:

  Recombinant protein of human sialic acid binding Ig-like lectin 1, sialoadhesin (SIGLEC1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6614

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BZZ2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_023068

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_075556