Siglec1 (NM_011426) Mouse Recombinant Protein

• Background:

  Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity) . Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Cd169; Siglec-1; Sn

• Gene ID:

  20612

• UniProt:

  Q62230, G3X8X6

• Accession Number mRNA:

  NM_011426

• Chromosomal Location:

  2 63.26 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  184 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Siglec1

• Species:

  Mouse

• Protein ID:

  NP_035556

• Overview:

  Purified recombinant protein of Mouse sialic acid binding Ig-like lectin 1, sialoadhesin (Siglec1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/20612

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q62230

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011426

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035556