TICAM2 (TMED7-TICAM2) (NM_001164469) Human Recombinant Protein

• Background:

  This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010]

• Synonyms:

  MyD88-4; TICAM-2; TICAM2; TIRAP3; TIRP; TRAM

• Gene ID:

  100302736

• UniProt:

  Q86XR7, Q9Y3B3, A0A0A6YYA0

• Accession Number mRNA:

  NM_001164469

• Chromosomal Location:

  5q22.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  21.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TMED7-TICAM2

• Species:

  Human

• Protein ID:

  NP_001157941

• Overview:

  Recombinant protein of human TMED7-TICAM2 readthrough (TMED7-TICAM2), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/100302736

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q86XR7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001164469

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001157941