Argonaute 2 (AGO2) (NM_001164623) Human Recombinant Protein

• Background:

  This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

• Synonyms:

  CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10

• Gene ID:

  27161

• UniProt:

  Q9UKV8

• Accession Number mRNA:

  NM_001164623

• Chromosomal Location:

  8q24.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  28769054

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  93.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AGO2

• Species:

  Human

• Protein ID:

  NP_001158095

• Overview:

  Purified recombinant protein of Homo sapiens eukaryotic translation initiation factor 2C, 2 (EIF2C2), transcript variant 2.

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/27161

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UKV8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001164623

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001158095