FOXL2 Mutant (C134W) Human Recombinant Protein

• Background:

  This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. [provided by RefSeq, Jul 2016]

• Synonyms:

  BPES; BPES1; PFRK; PINTO; POF3

• Gene ID:

  668

• Accession Number mRNA:

  NM_023067

• Chromosomal Location:

  3q22.3

• Expression System:

  HEK293

• Tag:

  Myc-DDK

• Concentration:

  >50 ug/mL as determined by microplate Bradford method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  38.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FOXL2

• Species:

  Human

• Protein ID:

  NP_075555.1

• Overview:

  Purified mutant recombinant protein of Human forkhead box L2 (FOXL2), mutation at (C134W)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/668

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_023067

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_075555.1