OLIG2 (NM_005806) Human Recombinant Protein

• Background:

  This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t (14;21) (q11.2; q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]

• Synonyms:

  BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17

• Gene ID:

  10215

• UniProt:

  Q13516

• Accession Number mRNA:

  NM_005806

• Chromosomal Location:

  21q22.11

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  12.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  OLIG2

• Species:

  Human

• Protein ID:

  NP_005797

• Overview:

  Purified recombinant protein of Human oligodendrocyte lineage transcription factor 2 (OLIG2), Met1-Arg120, with N-terminal His tag, expressed in E.coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10215

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13516

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005806

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005797