Olig2 (NM_016967) Mouse Recombinant Protein

• Background:

  Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain (PubMed:11955448, PubMed:12121626, PubMed:16908628) . Functions together with ZNF488 to promote oligodendrocyte differentiation (PubMed:16908628) . Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube (PubMed:11955448, PubMed:12121626) . Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (PubMed:11955448, PubMed:12121626) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AI604895; Bhlhb1; bHLHe19; Olg-2; Oligo2; RK17

• Gene ID:

  50913

• UniProt:

  Q9EQW6, Q542S0

• Accession Number mRNA:

  NM_016967

• Chromosomal Location:

  16 52.6 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  32.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Olig2

• Species:

  Mouse

• Protein ID:

  NP_058663

• Overview:

  Purified recombinant protein of Mouse oligodendrocyte transcription factor 2 (Olig2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/50913

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9EQW6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016967

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_058663