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Fxyd6 (BC042579) Mouse Recombinant Protein

CAT: 0882-PM49131M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM49131M5Size:20 µg
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Background
This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na, K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, Fxyd6, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., [email protected]., Jul 2006]
Overview
Purified recombinant protein of Mouse FXYD domain-containing ion transport regulator 6 (cDNA clone MGC:25545 IMAGE:3709336), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
0610030I18Rik; Php
Gene ID
59095
UniProt
Q9D164
Accession Number mRNA
BC042579
Chromosomal Location
9 A5.2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
10.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Fxyd6
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/59095
Uniprot URL
https://www.uniprot.org/uniprot/Q9D164
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC042579

UniProtKB · Q9D164

FXYD domain-containing ion transport regulator 6

FXYD6_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9D164
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Fxyd6
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q99NC3, Q9CXD0
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Technical term

Direct protein sequencingReference proteome

Biological process

Ion transportPotassium transportSodium transportSodium/potassium transportTransport

Ligand

PotassiumSodium

Domain

SignalTransmembraneTransmembrane helix

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