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Hmgn3 (BC005693) Mouse Recombinant Protein

CAT: 0882-PM49126M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM49126M5Size:20 µg
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Background
Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse high mobility group nucleosomal binding domain 3 (cDNA clone MGC:11574 IMAGE:3597594), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
TRIP7, HMGN3a, HMGN3b
Gene ID
94353
UniProt
Q9DCB1
Accession Number mRNA
BC005693
Chromosomal Location
9 E2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
10.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Hmgn3
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/94353
Uniprot URL
https://www.uniprot.org/uniprot/Q9DCB1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC005693

UniProtKB · Q9DCB1

High mobility group nucleosome-binding domain-containing protein 3

HMGN3_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9DCB1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Hmgn3
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q7M737, Q99JU1
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorDNA-binding

Cellular component

Nucleus

PTM

Phosphoprotein

Technical term

Reference proteome

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