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Cdc5l (BC003893) Mouse Recombinant Protein

CAT: 0882-PM46546M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM46546M5Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse cell division cycle 5-like (S. pombe) (cDNA clone MGC:6754 IMAGE:3593535), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1200002I02Rik; AA408004; PCDC5RP
Gene ID
71702
UniProt
Q6A068
Accession Number mRNA
BC003893
Chromosomal Location
17 B3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
73.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cdc5l
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/71702
Uniprot URL
https://www.uniprot.org/uniprot/Q6A068
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC003893

UniProtKB · Q6A068

Cell division cycle 5-like protein

CDC5L_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q6A068
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cdc5l
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q8K1J9
Protein keywords

Molecular function

ActivatorDNA-bindingRNA-binding

Biological process

Cell cycleDNA damageDNA repairmRNA processingmRNA splicingTranscriptionTranscription regulation

Domain

Coiled coilRepeat

Cellular component

CytoplasmNucleusSpliceosome

Technical term

Direct protein sequencingReference proteome

PTM

Isopeptide bondPhosphoproteinUbl conjugation

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