Cirbp (NM_007705) Mouse Recombinant Protein

• Background:

  Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Cirp; R74941

• Gene ID:

  12696

• UniProt:

  P60824

• Accession Number mRNA:

  NM_007705

• Chromosomal Location:

  10 39.72 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  18.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cirbp

• Species:

  Mouse

• Protein ID:

  NP_031731

• Overview:

  Purified recombinant protein of Mouse cold inducible RNA binding protein (Cirbp), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12696

• Uniprot URL:

  https://www.uniprot.org/uniprot/P60824

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007705

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_031731