Yaf2 (NM_024189) Mouse Recombinant Protein

• Background:

  Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2810021M11Rik

• Gene ID:

  67057

• UniProt:

  Q99LW6

• Accession Number mRNA:

  NM_024189

• Chromosomal Location:

  15 E3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  19.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Yaf2

• Species:

  Mouse

• Protein ID:

  NP_077151

• Overview:

  Purified recombinant protein of Mouse YY1 associated factor 2 (Yaf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/67057

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99LW6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_024189

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_077151