Nkiras2 (NM_028024) Mouse Recombinant Protein

• Background:

  Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2410003M04Rik; 4930527H08Rik; D630018G21Rik; KBRAS2

• Gene ID:

  71966

• UniProt:

  Q9CR56

• Accession Number mRNA:

  NM_028024

• Chromosomal Location:

  11 D

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  21.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Nkiras2

• Species:

  Mouse

• Protein ID:

  NP_082300

• Overview:

  Purified recombinant protein of Mouse NFKB inhibitor interacting Ras-like protein 2 (Nkiras2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/71966

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9CR56

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_028024

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_082300