Tesc (NM_021344) Mouse Recombinant Protein

• Background:

  Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na (+) /H (+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1010001A17Rik; 2410011K10Rik; TE-1

• Gene ID:

  57816

• UniProt:

  Q9JKL5, D0EM45

• Accession Number mRNA:

  NM_021344

• Chromosomal Location:

  5 57.84 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  24.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Tesc

• Species:

  Mouse

• Protein ID:

  NP_067319

• Overview:

  Purified recombinant protein of Mouse tescalcin (Tesc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/57816

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9JKL5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_021344

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_067319