Eif4e2 (BC049077) Mouse Recombinant Protein

• Background:

  Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:15153109) . Acts as a repressor of translation initiation (By similarity) . In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (PubMed:15153109) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2700069E09Rik; AI036339; AV129531; D0H0S6743E; Eif4el3

• Gene ID:

  26987

• UniProt:

  Q8BMB3

• Accession Number mRNA:

  BC049077

• Chromosomal Location:

  1 C5

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  29.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Eif4e2

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse eukaryotic translation initiation factor 4E member 2 (cDNA clone MGC:61339 IMAGE:5708556), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/26987

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8BMB3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC049077