F3 (NM_010171) Mouse Recombinant Protein

• Background:

  This gene encodes a membrane-bound glycoprotein that forms the primary physiological initiator of the blood coagulation process following vascular damage. The encoded protein binds to coagulation factor VIIa and the ensuing complex catalyzes the proteolytic activation of coagulation factors IX and X. Mice lacking encoded protein die in utero resulting from massive hemorrhaging in both extraembryonic and embryonic vessels. A severe deficiency of the encoded protein in mice results in impaired uterine homeostasis, shorter life spans due to spontaneous fatal hemorrhages and cardiac fibrosis. [provided by RefSeq, Aug 2015]

• Synonyms:

  AA409063; CD142; Cf-3; Cf3; TF

• Gene ID:

  14066

• UniProt:

  P20352, A0A0R4J088

• Accession Number mRNA:

  NM_010171

• Chromosomal Location:

  3 52.94 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  32.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  F3

• Species:

  Mouse

• Protein ID:

  NP_034301

• Overview:

  Purified recombinant protein of Mouse coagulation factor III (F3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/14066

• Uniprot URL:

  https://www.uniprot.org/uniprot/P20352

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010171

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034301