Memo1 (NM_133771) Mouse Recombinant Protein

• Background:

  May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  0610016J10Rik; D930048L02Rik

• Gene ID:

  76890

• UniProt:

  Q91VH6

• Accession Number mRNA:

  NM_133771

• Chromosomal Location:

  17 E2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  33.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Memo1

• Species:

  Mouse

• Protein ID:

  NP_598532

• Overview:

  Purified recombinant protein of Mouse mediator of cell motility 1 (Memo1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/76890

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q91VH6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_133771

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_598532