Hsd17b11 (NM_053262) Mouse Recombinant Protein

• Background:

  Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Dhrs8; Pan1b; retSDR2; SDR2

• Gene ID:

  114664

• UniProt:

  Q9EQ06

• Accession Number mRNA:

  NM_053262

• Chromosomal Location:

  5 E5

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  32.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Hsd17b11

• Species:

  Mouse

• Protein ID:

  NP_444492

• Overview:

  Purified recombinant protein of Mouse hydroxysteroid (17-beta) dehydrogenase 11 (Hsd17b11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/114664

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9EQ06

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_053262

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_444492