F11r (NM_172647) Mouse Recombinant Protein

• Background:

  Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11447115) . The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (PubMed:11447115) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (PubMed:9660867) . Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (By similarity) . Involved in platelet activation (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  9130004G24; AA638916; ESTM33; JAM; JAM-1; JAM-A; Jcam; Jcam1; Ly106

• Gene ID:

  16456

• UniProt:

  O88792

• Accession Number mRNA:

  NM_172647

• Chromosomal Location:

  1 79.43 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  32.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  F11r

• Species:

  Mouse

• Protein ID:

  NP_766235

• Overview:

  Purified recombinant protein of Mouse F11 receptor (F11r), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16456

• Uniprot URL:

  https://www.uniprot.org/uniprot/O88792

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_172647

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_766235