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Bub3 (NM_009774) Mouse Recombinant Protein

CAT: 0882-PM47262M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM47262M5Size:20 µg
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Background
This gene encodes a component of the mitotic spindle assembly complex. The encoded protein is involved in the regulation of chromosome segregation during oocyte meiosis. Disruption of this gene results in the accumulation of mitotic errors and is lethal in the embryonic stage. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Overview
Purified recombinant protein of Mouse BUB3 mitotic checkpoint protein (Bub3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AU019800; AU021329; AU043350; AW146323; C78067
Gene ID
12237
UniProt
Q9WVA3
Accession Number mRNA
NM_009774
Chromosomal Location
7 74.36 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
37 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Bub3
Species
Mouse
Protein ID
NP_033904
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12237
Uniprot URL
https://www.uniprot.org/uniprot/Q9WVA3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009774
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033904

UniProtKB · Q9WVA3

Mitotic checkpoint protein BUB3

BUB3_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9WVA3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Bub3
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
P97397, Q6ZWM5
Protein keywords

PTM

AcetylationADP-ribosylationIsopeptide bondPhosphoproteinUbl conjugation

Biological process

Cell cycleCell divisionChromosome partitionMeiosisMitosis

Cellular component

CentromereChromosomeKinetochoreNucleus

Technical term

Reference proteome

Domain

RepeatWD repeat

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