Trub2 (NM_145520) Mouse Recombinant Protein

• Background:

  Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  G430055L02Rik

• Gene ID:

  227682

• UniProt:

  Q91WG3

• Accession Number mRNA:

  NM_145520

• Chromosomal Location:

  2 B

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  36.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Trub2

• Species:

  Mouse

• Protein ID:

  NP_663495

• Overview:

  Purified recombinant protein of Mouse TruB pseudouridine (psi) synthase family member 2 (Trub2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/227682

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q91WG3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_145520

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_663495