Fnta (NM_008033) Mouse Recombinant Protein

• Background:

  Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  FTA

• Gene ID:

  14272

• UniProt:

  Q61239, Q541Z2

• Accession Number mRNA:

  NM_008033

• Chromosomal Location:

  8 14.27 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  44 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Fnta

• Species:

  Mouse

• Protein ID:

  NP_032059

• Overview:

  Purified recombinant protein of Mouse farnesyltransferase, CAAX box, alpha (Fnta), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/14272

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q61239

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008033

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032059