Bis-PEG2-acid

• Description :

  Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/bis-peg2-acid.html

• Purity :

  98.0

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)CCOCCOCCC(O)=O

• Molecular Formula :

  C8H14O6

• Molecular Weight :

  206.19

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62 (20) :9281-9298.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers

• CAS Number :

  [19364-66-0]