Bis-PEG2-acid

• Description:

  Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bis-peg2-acid.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)CCOCCOCCC(O)=O

• Molecular Formula:

  C8H14O6

• Molecular Weight:

  206.19

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62 (20) :9281-9298.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers

• CAS Number:

  19364-66-0