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Bis-PEG2-acid

CAT: 0804-HY-112559-01Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112559-01Size:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
CAS Number
19364-66-0
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-peg2-acid.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(O)CCOCCOCCC(O)=O
Molecular Formula
C8H14O6
Molecular Weight
206.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62 (20) :9281-9298.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers