Casp9 (NM_015733) Mouse Recombinant Protein

• Background:

  This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]

• Synonyms:

  AI115399; APAF-3; AW493809; Casp; CASP-9; Caspase-9; ICE-; ICE-LAP6; Mch6

• Gene ID:

  12371

• UniProt:

  Q8C3Q9

• Accession Number mRNA:

  NM_015733

• Chromosomal Location:

  4 D3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  50 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Casp9

• Species:

  Mouse

• Protein ID:

  NP_056548

• Overview:

  Purified recombinant protein of Mouse caspase 9 (Casp9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12371

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8C3Q9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_015733

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_056548