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Zcchc8 (BC013555) Mouse Recombinant Protein

CAT: 0882-PM46181M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM46181M5Size:20 µg
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Background
Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. May be involved in pre-mRNA splicing.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse zinc finger, CCHC domain containing 8 (cDNA clone MGC:19353 IMAGE:4238634), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
5730565F05Rik
Gene ID
70650
UniProt
Q9CYA6
Accession Number mRNA
BC013555
Chromosomal Location
5 F
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
50.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Zcchc8
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/70650
Uniprot URL
https://www.uniprot.org/uniprot/Q9CYA6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC013555

UniProtKB · Q9CYA6

Zinc finger CCHC domain-containing protein 8

ZCHC8_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9CYA6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Zcchc8
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q3TK71, Q8CCB7, Q91WQ1
Protein keywords

PTM

AcetylationPhosphoprotein

Domain

Coiled coilZinc-finger

Ligand

Metal-bindingZinc

Biological process

mRNA processingmRNA splicing

Cellular component

NucleusSpliceosome

Technical term

Reference proteome

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