Dok1 (NM_010070) Mouse Recombinant Protein

• Background:

  DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3 (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AW557123; p62DOK

• Gene ID:

  13448

• UniProt:

  P97465, Q3UWF9

• Accession Number mRNA:

  NM_010070

• Chromosomal Location:

  6 35.94 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  52.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Dok1

• Species:

  Mouse

• Protein ID:

  NP_034200

• Overview:

  Purified recombinant protein of Mouse docking protein 1 (Dok1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/13448

• Uniprot URL:

  https://www.uniprot.org/uniprot/P97465

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010070

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034200