Tcf4 (BC014293) Mouse Recombinant Protein

• Background:

  Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') . Isoform 2 inhibits MYOD1 activation of the cardiac alpha-actin promoter. Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription. May have a regulatory function in developmental processes as well as during neuronal plasticity.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  ME2, ITF-2, SEF-2, MITF-2A, MITF-2B, TFE, E2-2, E2.2, ITF2, SEF2, ASP-I2, ITF-2b, SEF2-1

• Gene ID:

  21413

• UniProt:

  Q60722

• Accession Number mRNA:

  BC014293

• Chromosomal Location:

  18 E2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  54.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Tcf4

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse transcription factor 4 (cDNA clone MGC:13998 IMAGE:4014231), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/21413

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q60722

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC014293