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Dbr1 (BC006661) Mouse Recombinant Protein

CAT: 0882-PM45739M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM45739M5Size:20 µg
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Background
Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse cDNA clone MGC:6384 IMAGE:3501390, complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AW018415
Gene ID
83703
UniProt
Q923B1
Accession Number mRNA
BC006661
Chromosomal Location
9 E3.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
61.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dbr1
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83703
Uniprot URL
https://www.uniprot.org/uniprot/Q923B1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC006661

UniProtKB · Q923B1

Lariat debranching enzyme

DBR1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q923B1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Dbr1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
3.1.4.-
Processing
—
Secondary accessions
Q8C1T9, Q8C7J7, Q99MT1
Protein keywords

PTM

AcetylationPhosphoprotein

Molecular function

Hydrolase

Ligand

IronManganeseMetal-bindingZinc

Biological process

mRNA processing

Cellular component

Nucleus

Technical term

Reference proteome

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