Hax1 (BC006688) Mouse Recombinant Protein

• Background:

  Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  HAX-1, mHAX-1s, SIG-111

• Gene ID:

  23897

• UniProt:

  O35387

• Accession Number mRNA:

  BC006688

• Chromosomal Location:

  3 F1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  31.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Hax1

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse HCLS1 associated X-1 (cDNA clone MGC:5838 IMAGE:3582652), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23897

• Uniprot URL:

  https://www.uniprot.org/uniprot/O35387

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC006688