Setd3 (BC019973) Mouse Recombinant Protein

• Background:

  Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30626964) . Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964) . Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2610102I01Rik; 2610305M23Rik; 6030490B17Rik; D12Ertd771e

• Gene ID:

  52690

• UniProt:

  Q91WC0

• Accession Number mRNA:

  BC019973

• Chromosomal Location:

  12 59.23 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  90.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Setd3

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse SET domain containing 3 (cDNA clone MGC:28544 IMAGE:4195130), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/52690

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q91WC0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC019973