SETD3 Rabbit pAb (APR27937N)

CAT: 0882-APR27937N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR27937N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SETD3 Rabbit pAb (APR27937N) .

Synonyms

SETD3; C14orf154

Gene ID

84193

UniProt

Q86TU7

Cellular Locus

Nucleus

Applications

WB (Homo sapiens)

Dilution

WB 1:500 - 1:2000 IP 1:50 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 32kDa/33kDa/67kDa Observed MW: 70kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=84193

Uniprot URL

https://www.uniprot.org/uniprot/Q86TU7

AA Sequence

MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVN

UniProtKB · Q86TU7

Actin-histidine N-methyltransferase

SETD3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q86TU7
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SETD3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.1.1.85
Processing: —
Secondary accessions: A0PJU3, A5PLP0, B4DZE8, Q0VAQ2, Q659C0, Q86TU8, Q96GY9, Q9H5U5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Actin-bindingMethyltransferaseTransferase

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

PTM

PhosphoproteinUbl conjugation

Ligand

S-adenosyl-L-methionine

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