Ralbp1 (NM_009067) Mouse Recombinant Protein

• Background:

  Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Rip1; RLIP76

• Gene ID:

  19765

• UniProt:

  Q62172

• Accession Number mRNA:

  NM_009067

• Chromosomal Location:

  17 35.26 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  75 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ralbp1

• Species:

  Mouse

• Protein ID:

  NP_033093

• Overview:

  Purified recombinant protein of Mouse ralA binding protein 1 (Ralbp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/19765

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q62172

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009067

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033093