RALBP1 Mouse Monoclonal Antibody [Clone ID: LBI6E8]

• Background:

  Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin

• Synonyms:

  RIP1; RLIP1; RLIP76

• Gene Name:

  RalA binding protein 1

• Gene ID:

  10928

• UniProt:

  Q15311

• Conjugation:

  Unconjugated

• Related Pathways:

  Pancreatic cancer, Pathways in cancer

• Field of Research:

  Pancreatic cancer, Pathways in cancer

• Concentration:

  0.85 mg/ml

• Dilution:

  WB 1:2000, IHC 1:50, IF 1:100, IP: 4ug/mL

• Form:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  RALBP1

• Overview:

  Anti-RALBP1 (RIP1) mouse monoclonal antibody, clone LBI6E8

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=10928

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15311