Map3k20 (NM_023057) Mouse Recombinant Protein

• Background:

  Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways (PubMed:11042189) . Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14 (By similarity) . Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (By similarity) . Involved in limb development (PubMed:26755636) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AV006891; B230120H23Rik; MLTK; MLTKalpha; MLTKbeta; Zak

• Gene ID:

  65964

• UniProt:

  Q9ESL4

• Accession Number mRNA:

  NM_023057

• Chromosomal Location:

  2 C3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  91.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Map3k20

• Species:

  Mouse

• Protein ID:

  NP_075544

• Overview:

  Purified recombinant protein of Mouse mitogen-activated protein kinase kinase kinase 20 (Map3k20), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/65964

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9ESL4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_023057

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_075544