Cdhr2 (NM_001033364) Mouse Recombinant Protein

• Background:

  Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Gm624; PC-LKC; Pcdh24

• Gene ID:

  268663

• UniProt:

  E9Q7P9

• Accession Number mRNA:

  NM_001033364

• Chromosomal Location:

  13 B1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  143.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cdhr2

• Species:

  Mouse

• Protein ID:

  NP_001028536

• Overview:

  Purified recombinant protein of Mouse cadherin-related family member 2 (Cdhr2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/268663

• Uniprot URL:

  https://www.uniprot.org/uniprot/E9Q7P9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001033364

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001028536