Adam11 (NM_009613) Mouse Recombinant Protein

• Background:

  This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. The protein encoded by this gene is believed to lack metalloproteinase activity due to the lack of a critical catalytic motif. Mice lacking the encoded protein exhibit defects in spatial learning, motor coordination and altered perception of pain. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing. [provided by RefSeq, May 2016]

• Synonyms:

  AW060611; Mdc

• Gene ID:

  11488

• UniProt:

  Q9R1V4, Q7TQG7, Q3TZE2

• Accession Number mRNA:

  NM_009613

• Chromosomal Location:

  11 66.48 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  84.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Adam11

• Species:

  Mouse

• Protein ID:

  NP_033743

• Overview:

  Purified recombinant protein of Mouse a disintegrin and metallopeptidase domain 11 (Adam11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11488

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9R1V4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009613

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033743