Gp2 (NM_025989) Mouse Recombinant Protein

• Background:

  Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participates to the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2310037I18Rik; AV060639

• Gene ID:

  67133

• UniProt:

  Q9D733, A0A0R4J0B9

• Accession Number mRNA:

  NM_025989

• Chromosomal Location:

  7 63.88 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  59.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Gp2

• Species:

  Mouse

• Protein ID:

  NP_080265

• Overview:

  Purified recombinant protein of Mouse glycoprotein 2 (zymogen granule membrane) (Gp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/67133

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9D733

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_025989

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_080265