Faap20 (NM_001190445) Mouse Recombinant Protein

• Background:

  Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1 (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2610002J02Rik

• Gene ID:

  67513

• UniProt:

  Q3UN58

• Accession Number mRNA:

  NM_001190445

• Chromosomal Location:

  4 E2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  20.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Faap20

• Species:

  Mouse

• Protein ID:

  NP_001177374

• Overview:

  Purified recombinant protein of Mouse Fanconi anemia core complex associated protein 20 (Faap20), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/67513

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q3UN58

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001190445

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001177374