Itga2b (NM_010575) Mouse Recombinant Protein

• Background:

  Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AI172977; alphaIIb; CD41; CD41B; GpIIb

• Gene ID:

  16399

• UniProt:

  Q9QUM0

• Accession Number mRNA:

  NM_010575

• Chromosomal Location:

  11 66.29 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  112.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Itga2b

• Species:

  Mouse

• Protein ID:

  NP_034705

• Overview:

  Purified recombinant protein of Mouse integrin alpha 2b (Itga2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16399

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9QUM0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010575

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034705