Dmc1 (NM_010059) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins) . Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. In mouse, deficiency of this gene causes infertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

• Synonyms:

  Dmc1h; Lim15; Mei1; Mei11; sg; sgdp

• Gene ID:

  13404

• UniProt:

  Q61880, Q14AN8

• Accession Number mRNA:

  NM_010059

• Chromosomal Location:

  15 37.79 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  37.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Dmc1

• Species:

  Mouse

• Protein ID:

  NP_034189

• Overview:

  Purified recombinant protein of Mouse DNA meiotic recombinase 1 (Dmc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/13404

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q61880

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010059

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034189