Fxn (NM_008044) Mouse Recombinant Protein

• Background:

  Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe (2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe (2+) to Fe (3+) ; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  FA; FARR; Frda; X25

• Gene ID:

  14297

• UniProt:

  O35943, Q3TV21

• Accession Number mRNA:

  NM_008044

• Chromosomal Location:

  19 B

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  23.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Fxn

• Species:

  Mouse

• Protein ID:

  NP_032070

• Overview:

  Purified recombinant protein of Mouse frataxin (Fxn), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/14297

• Uniprot URL:

  https://www.uniprot.org/uniprot/O35943

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008044

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032070