Cd74 (NM_010545) Mouse Recombinant Protein

• Background:

  Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  CLIP; DHLAG; HLADG; Ia-GAMMA; Ii

• Gene ID:

  16149

• UniProt:

  Q545Y5

• Accession Number mRNA:

  NM_010545

• Chromosomal Location:

  18 34.41 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  24.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cd74

• Species:

  Mouse

• Protein ID:

  NP_034675

• Overview:

  Purified recombinant protein of Mouse CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16149

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q545Y5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010545

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034675