Ddrgk1 (NM_029832) Mouse Recombinant Protein

• Background:

  Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (By similarity) . May also play a role in the cellular response to endoplasmic reticulum stress (PubMed:21494687) . Plays a role in cartilage development through SOX9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator (PubMed:28263186) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1110001I20Rik; 2600009E05Rik; AI326138; Ufbp1

• Gene ID:

  77006

• UniProt:

  Q80WW9

• Accession Number mRNA:

  NM_029832

• Chromosomal Location:

  2 F1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  36 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ddrgk1

• Species:

  Mouse

• Protein ID:

  NP_084108

• Overview:

  Purified recombinant protein of Mouse DDRGK domain containing 1 (Ddrgk1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/77006

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q80WW9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_029832

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_084108