Ins2 (NM_001185083) Mouse Recombinant Protein

• Background:

  This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked heterodimeric functional protein that is stored in secretory granules. An increase in blood glucose levels, among others, induces the release of insulin from the secretory granules. Mice deficient in the functional hormone encoded by this gene develop diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

• Synonyms:

  AA986540; In; Ins-2; InsII; Mod; Mody; Mody4

• Gene ID:

  16334

• UniProt:

  P01326, Q5EEX1

• Accession Number mRNA:

  NM_001185083

• Chromosomal Location:

  7 88.0 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  12.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ins2

• Species:

  Mouse

• Protein ID:

  NP_001172012

• Overview:

  Purified recombinant protein of Mouse insulin II (Ins2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16334

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01326

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001185083

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001172012