Α-Tubulin Mouse mAb (AMM22050N)

• Background:

  Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  TUBA4A; ALS22; H2-ALPHA; TUBA1

• Gene ID:

  7277

• UniProt:

  P68366

• Cellular Locus:

  Cytoplasm, cytoskeleton

• Applications:

  WB (Homo sapiens, Rattus norvegicus, Mus musculus, Danio rerio, Artemisia scoparia, Tegillarca granosa) IF (Homo sapiens, Mus musculus) IP (Homo sapiens)

• Dilution:

  WB 1:5000 - 1:10000 IHC 1:200 - 1:500 IF 1:100 - 1:200 IP 1:100 - 1:200

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 48kDa/49kDa Observed MW: 50kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality α-Tubulin Mouse mAb (AMM22050N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7277

• Uniprot URL:

  https://www.uniprot.org/uniprot/P68366

• AA Sequence:

  Email for sequence